Dear Pada,
I also used Spysweeper which ugraded on its own through auto updates to Webroot internet security essentials(WISE, Webroot humor?) It does create about 59-60MB of temp files which CCleaner and Webroot's Window Washer failed to clean. After 3 irrelevant replys from WR, I unistalled WISE and reinstalled Spysweeper choosong not to chek for updates during the install. The temp files are gone now.
WISE indeed uses these temp files to do it's dubious job, but I had Norton Intenet Security and did not need another firewall ans AV progam to conflict. It is best only to have one of each running or there can be conflicts and (shudder) BSOD's.
No cleaning tool I know of will clean temp files if they are in use, such as the index.dat IE files.