Thanks Alan_B.
Actually, I already found what you have said to be true. So, last night, I developed a different strategy that appears to be working. I am systematically moving all of my files that are already on my drive to the end of the drive. By doing a search of each folder, I can check, designating a move to the end of the drive, all of the contents of the folder. Sometimes I need to separately move a file in the folder with a different name. It is usually a very small file that is moved to the block nearest the end of drive that still has free space. This way, I am compacting all of my compressed files (the drive is compressed) using all available free space, maximizing the data that can be contained on the external drive. All files, so moved, are defragmented and the free spaces they are moved to seem to be defragmented, too.
When I have moved all of the files presently on the drive to the end, I will want new files I am moving to the drive to be compactly copied to the beginning of the drive. Here is my question:
Should I defragment the free space (not allowing fragmentation option) before adding files to the beginning of the drive that has been cleared of all files by moving them to the end?
In other words, after I have moved all existing files to the end, will the free space left behind, which was previously 'free space defragmented' now be fragmented again and in need of another defragmentation?
Or will Defraggler automatically defragment the free space as the new files are added to the beginning of the drive? Even more important for me to know is, if I do defragment the free space, will Defraggler disturb, in any way, the files I have compactly moved to the end of the drive? Will it move any of those files away from the end of the drive or cause them to be fragmented or otherwise moved about?