Hi James!
You need to first setup the option on which settings you want to clean i.e. cookies, temporary internet files.
Next step to do is to go to Options > Advanced > Make sure ‘Save all settings to INI file’ is ticked.
You need now to go to Start > Programs > Accessories > System Tools > Create Basic Task > Type name of the task i.e. CC cleaner auto > Choose weekly or daily > Choose time of day you like for it to run > Start Program > Go to C:\Program Files\CCleaner\CCleaner.exe and run it > Add /auto switch on the Add Arguments box > Finish > Choose Run with highest privelegdes. Try to read here for a more detailed approach http://www.techyv.com/questions/how-run-ccleaner-automatically