No, I'm not using a winapp2.ini file. When the slowdown happens, my hard drive activity goes way up, so it looks to me like it may be doing a full rebuild of the application information it needs to proceed.
I chose to post on this thread because the poster just prior to me had an identical issue and program version within a couple of weeks which had not yet been satisfactorily resolved.
Also slow loading several minutes. It's not consistent, though. Another symptom is that I get a "busy" symbol when I mouseover the section of the program that lists Windows and Applications. v3.05.1409.