Defraggler is locking any USB disk drive I plug in while the program is running. I can't use the "Safely Remove Hardware" feature of Windows to eject the drive until I close the program.
That particular stream seems to be from Microsoft Indexing Service. Seems to be a thumbnail, and it's also larger than the source file itself.
Time to use Sysinternals Streams and delete that crap.
While defragging, I saw some file paths like "C:\directory\filename.ext:|Q30lsldxJoudresxAaaqpcawXc". What does that string after the filename mean? (begins with colon and pipe character) Is that indicating an alternate data stream or something?