Most of these files are time stamped prior to 7/2008 with some going back to 2006. The majority are .tmp files with a few .txt, .csv, .log, etc. Most of the directories end in .tmp while some have names like {F03DCCCE-243B-4944-A808-35A74C2E39C1}. I know I can manually delete the files or be safe and rename them but I am curious why CCleaner doesn't delete them??? The "48 hour" should have no effect since 98% of the files are dated prior to that. It's as if CCleaner doesn't know that the directory exists???
It looks like some of the files are involved with setups/installs while others are used by running programs that are using temp files.