I have a similar problem. I run XP Home. Version 1.41.385 worked perfectly, every version since then (including the current 1.41.544) shuts down if you right click "Run Cleaner" from the Recycle bin.
It appears to clean everything, but after doing so, it generates an error message and then closes. Simple solution was to re-install 1.38.485, however, this makes no sense. Nothing else has been changed on the machine (firewall, adware removers, antivirus, browsers, etc.). Anyone have any ideas ??
BTW, the "user" as which I log in has full administrative rights on the machine, so that is also not the answer... sorry...
Forgot... this is a neat piece of software and works really well! Except for this problem (and the older version is really OK) I have had absolutely no problems with it! Thanks!!