On Vista SP2 RTM x64 Business, CCleaner does not show the files that are in C:\Windows\System32\Config folder so that a specific file can be included in the Options>Include cleaning of CCleaner. Oddly, it does show files that are in subfolders within folder Config.
jv16 Powertools registry cleaner stores some large backup files in the Config folder during its Registry compacting. These are such as components.bak_jv16pt, software.bak_jv16pt, and system.bak_jv16pt. I would like to clean the backup files via CCleaner on 64-bit.