Why is there always an ActiveX...... registry issue every time I fix all issues? It doesn't go away.
ActiveX/COM Issue LocalServer32\C:\Windows\SysWOW64\Speech_OneCore\Common\SpeechRuntime.exe -ToastNotifier HKCR\CLSID\{265b1075-d22b-41eb-bc97-87568f3e6dab}
It is needed by Windows, and so Windows will always put it back if/when you remove it, you can tell CCleaner to ignore it. (better yet don't use the Registry Cleaner on Windows 10 at all).
See this:
There are various things that will come straight back after cleaning, and there are reasons why they do that.
For a fuller explanation of why, and what you can do to stop some of it see this: