This type of key (beginning with a I) is usually tied to your antimalware software. As you would not want softwares to easily disable your antivirus, it does not register itself as a connected registry entry and thus programs, like Ccleaner, will see it as a registry "issue".
Right click it and choose exclude. Then read my signature and perhaps save yourself grief by not cleaning everything suggested by ccleaner, or especially any competitive registry cleaner (not because my personal bias but because it is the most gentle registry cleaner out there, with most others showing more entries and thus are more likely to break a PC when cleaning blindly)