Need help regarding Registry Cleaning

I ran my ccleaner this morning, all was fine. I then went to the 'registry' tab & clicked on 'scan for issues'. The list is quite long. I saved the report to a text file. I honestly have no idea what I should do here. It has a tab that says "fix selected issues". I don't know if I should click the tab and/or what boxes need to be checked or unchecked so I don't break anything.

I would greatly appreciate any help with this. I can even send the file if you're interested.

Thank You & God Bless

moderator Nergal's advice:

DON'T JUST CLEAN EVERYTHING THAT'S CHECKED OFF.

Do your Registry Cleaning in small bits (at the very least Check-mark by Check-mark)

ALWAYS BACKUP THE ENTRY, YOU NEVER KNOW WHAT YOU’LL BREAK IF YOU DON’T.

And if you decide to "fix" the issues make a System Restore Point beforehand, so you can very easily undo any changes.