I know this was discussed in 2011 but I have tried to sort it out with no success.
I run Windows 7 64bit. Love Defraggler and found it to work perfectly for me but I would love the ability to defrag a folder or move a large file to the end of the drive specifically with a right-click from Explorer.
First I have tried to get it to work on both 32 and 64bit versions by doing the following:-
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I went into the software and disabled save settings to .ini file (I set that up when I first installed it)
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Deleted the .ini file from the Defraggler directory
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Started the programme both with a right-click ‘Run As Administrator’ and from the Start Menu where I then set ‘Run As Administrator’ as a launch option in the shortcut Properties>Advanced setting.
In all cases the option to Enable Shell Extension is greyed out.
The only options I have checked in the Defraggler Advanced tab are now are the Cache Analyses and Use Custom Fragmentation (for which I have not changed default options).
I’ve tried checking them all and the Enable Shell Extensions just does not become available.
I tried the only thing I didn't do before and that was to remove it and reinstall it.
During the reinstall I left the 'Defraggler in Explorer' (or similar) option checked - then the right-click menu items were there - but I still had no option to move large files to the end of the drive, and this is the primary reason why I wanted it to work and wanted to use this software.
UPDATE: Seems like I read that this software would do that not too long ago, I am unable to find the page now but I am pretty sure that it cannot send large files to the end of a drive from within Explorer - this is a pity as I liked the software otherwise. I make regular Acronis images and would have loved this feature rather than having to run Defraggler to do a disk defrag every time I make a new image.
Perhaps in the future this will be an included option along with sending entire folders to the end of the drive...I will keep checking and install again if it does.