When I "Analyze Registry" CC comes up with two full pages of identified issues (about 50). I "Fix all selected issues" and they disappear. But the same 50 issues (or almost the same) reappear when I again analyze the registry. Attached are screenshots.
Please take the time to read my signature as it will give you some suggestions in using ccleaner's (or any) registry section. especially the part that says not to clean anything you don't know what it is.
For instance most of those entries beginning with I (such as IRoamRemoteStore) are probably your antivirus.