What is happening? If I go to uninstall defraggler, it will not let me... Somehow, a message appears from time to time stating that defraggler is running in the background. Why is it running in the background? how can I stop it? I would like to uninstall it and start all over but the system will not let me uninstall. A messages comes up: "Windows cannot access the specified device, path, or file. You may not have permission to access this item
Would you like to give a bit more info such as your operating system and also the version of defraggler.
Also how are you trying to uninstall it?
Have you tried uninstalling in safe mode or using Unlocker?