I would not worry at all.
Virus Total is like any other diagnostic tool in that you have to have some knowledge of what the results it gives actually mean.
VT can only give you information, you have to check that information and decide for yourself if it is relevent to you.
If you use VT regularly then you will know that False Positives often happen, and that 1 detection out of 68 is almost certainly a False Positive.
(In fact 4 or 5 out of that many results wouldn't bother me unduly).
Look at it the other way round - 67 out of 68 AVs have said that CCsetup614.exe is clean and is safe to use.
Minimal detections like that on VT usually come from little known and/or specialist AVs - and that is what is happening here.
In this case the one particular AV in your screenshot that flagged CCsetup614.exe is Deep Instinct.
Deep Instinct is intended for "endpoint" security, ie. business and large organisation networks that need extra checks for if an employee/user tries to install something that is not meant for use on a networked system.
https://www.deepinstinct.com/endpoint-security
CCleaner is meant for home (or small business) use, it is not designed for use on networked systems.
CCleaner Cloud is the edition for use with network endpoints, if a business chooses to use it.
So it is not surprising at all that an AV meant for network endpoints would flag up a home use cleaner app which can access system files to clear them, as well as access other user accounts in some circumstances - things which you may want to do at home, but should not be doing on a business network.
(We had a post here recently where a company's employee had tried to do just that, and their endpoint security rejected it and threw up multiple warning flags to their IT department, as it should on a business network).
So in the end it is your choice how to interpret the VT result and what to do with the information it gives you.
Mostly that comes from experience of using it and double checking what it says for yourself.