That's what I saw the when I ran CCleaner for the very first time on a machine.
Every time I clicked Analyze, I'd see the same number again. It was only after I hit Run Cleaner, waited for the cleanup to complete (removed about 2-4 gigabytes) and hit Analyze again, that CCleaner started reporting the correct number again.
I didn't use a custom winapp2.ini. The computer in question had several network drives attached but I don't think that had anything to do with this because I explicitly excluded them, just in case.