CCleaner 3.10.1525 never cleans my Chrome cache, though it does properly clean everything else.
It always reports 0KB in the Chrome cache whether checked (in the GUI I mean) or not, and of course never cleans anything.
The details: it's Win7x64 on a Dell XPS 8100 8GB (Core i7/860). What's worth noting is that C: is an SSD and I manually redirect the Google directory to D:\Google (D: is a regular HDD) using a directory symbolic link in my %USERPROFILE%\AppData\Local directory. So Chrome thinks it's installed on C: but it's actually not thanks to the symbolic link. (Maybe that's confusing CCleaner?)