I think I got the same problem when I updated the portable version from 5.43 to 5.44 (I already reported it here). It starts, the GUI is shown for a second and then it just "disappears". In the Windows event log it can be seen that CCleaner crashed (it also shows ntdll.dll as the Fault Module Name there). I use Windows 10 x64 1803 (Build 17143.137) and Kaspersky 19.0.01088(a). Version 5.44 is therefore completely unusable for me.
In a virtual machine with Windows 10 x32 1803 and Avast Free it works without a problem (version 5.42 also worked there).
I would like to add that I have KIS 19.0.0.1088a and ccleaner 5.44.162.6575 (windows 7) and I am experiencing this immediate crash upon attempt to launch too; it flashes the UI for the briefest instant and then closes without an error or anything (nothing in the windows event log either)
<div class="ipsQuote_contents">
<p>
I would like to add that I have KIS 19.0.0.1088a and ccleaner 5.44.162.6575 (windows 7) and I am experiencing this immediate crash upon attempt to launch too; it flashes the UI for the briefest instant and then closes without an error or anything (nothing in the windows event log either)
</p>
</div>
<div class="ipsQuote_contents">
<p>
See here
</p>
<p>
<a href="<___base_url___>/topic/52058-ccleaner-v543-close-on-clean-work-around/" rel="">https://forum.piriform.com/topic/52058-ccleaner-v543-close-on-clean-work-around/</a>
</p>
</div>
The problem is that CCleaner 5.44 crashes immediately so the setting can't be set. I also tried to set the setting in CCleaner 5.43 and then use the .ini file with CCleaner 5.44, but it has no effect. This workaround also had no effect for me before with CCleaner 5.42, the only thing that helped was reinstalling Kaspersky.
CCleaner 5.44 introduced pop-up ads, I wonder if this has anything to do with it.
I just wanted to report that CCleaner 5.44 now somehow works with Kaspersky Anti-Virus 2019 v19.0.0.1088(a). A few days ago it still crashed right at the start. So maybe Kaspersky released an update that fixed this?