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I have same issue with CCleaner 5.66 Portable disappears but non-portable is okay ;)

OS: Win 10.0.19041.208

Antivirus : Comodo Internet security + DB 32387

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5.66 for me keeps starting with Windows, in the task tray, despite disabling startup in the options. I even went as far as to look at all possible "startup" variants in Windows using an application called Autoruns, and CCleaner shows up in there under Scheduler, but in CCleaner options (free version), there's no way to change scheduler options. I removed CCleaner from scheduler using Autoruns and Windows Scheduler itself, but CCleaner just adds it back and runs on the next startup anyway. Had to uninstall. 

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@sidthefinger, @sladek

Update your Antivirus definitions, some are being slow to update automatically (due to everyone at the AV company working at home because of Covid-19?).

Also see here: https://community.ccleaner.com/topic/58113-mcafee-and-eset-nod32-false-postive-for-ccleaner-566-consolidated-thread/

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