Since updating to Windows Home v1803 I find that after running CCleaner v5.43.6522 (64-bit), when I next go to CClean it has actually been removed. The shortcuts state that there is no program to run and I have to go to my Download folder to re-install.
Any ideas on what has caused this and is there a fix please?
All AVs update their definitions and detection methods daily, sometimes 2, 3, more, times a day (at least all the good ones do).
And occasionally mistakes get made and things get blacklisted that shouldn't be.
I'm not familiar with SecureAnywhere, but this is their webpage about checking what it has quarantined: https://www.webroot.com/En_US/SecureAnywhere/PC/Content/C5_Quarantine/CH5a_ManagingQuarantine.htm
If you do find that it has quarantined CCleaner then you should restore it,