I forgot to mention I also disabled Security Center from warning me about Automatic Updates being turned off.
Malwarebytes will want to remove that disable since malware can also do the same, it see's it as threat so I have to exclude it in Malwarebytes since I myself did the system modification.
This is what I did maybe different in Vista though, I'm not for sure, but I get no warnings from Security Center:
the 1. easy way is as hazelnut used. (deactivate windows update -not the service, one click at the taskbar to close the warning in the taskbar)
the 2. easy way is to disable all warnings from vista security center.
--> right on the security center --> change the security center notification method --> dont send notification and dont display the icon (not recommended)
specially for notifications about windows update, there is no option available in vista.