What boxes are safe to checkmark under the Advanced section?

I was just curious on what all can be checked under the Advanced tab? As well as the 4 unchecked boxes under the System tab. I'm trying to free up much space as possible.

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I personally don't have anything ticked there although I sometimes tick, clean and then untick the Tray notification cache to clean out entries from uninstalled software.

More info here

https://www.piriform.com/docs/ccleaner/ccleaner-rules/windows-tab/advanced-windows-files

I have a few personal INCLUDEs and EXCLUDEs so I have Custom Files and Folders ticked.

I used to also have Old Prefetch data ticked, but since I got the SSD, I don't need it ticked as I've turned that Service off.

Otherwise the rest are unticked.

With the possible exception of Windows Event Logs which may eventually add up to a few MiBs at best, all the others combined would probably only add up to KiBs of reclaimed space.

my personal settings, so i never had any problems.

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+ include following folders/files

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but the last red arrow only makes sense if you use the "options --> include" function. (as ex: all kind of user-temp-folders)