I do not have Vista but I do like Tweak UI for XP
http://www.winvistaclub.com/e52.htmlTweak UI For Windows Vista Released at S Asia MVP Meet 2008.At the recently concluded South Asia MVP Meet 2008 held at Goa, between 14-18th November 2008, Ultimate Windows Tweaker, a Tweak UI for Windows Vista was released by Howard Lo, Microsoft's Regional Team Manager (APAC), in the presence of Abhishek Kant, South Asia ? MVP Lead and Abhishek Baxi, MVP Program Specialist. Earlier during the Meet, Pradeep Parappil - Program Manager Lead (Windows) gave an excellent presentation on Windows 7.