I enable the option of skipping user account control warning, but then I check again, and it's disabled automatically. Not even closing or restarting PC, but simply minimizing Speccy to tray disables it automatically.
It's working OK here.
I see you have the ini file selected, it maybe something to do with that? (Although creating an ini here I can't see any setting for skip UAC, I think it may be a registry entry).
The best I can suggest is uninstalling Speccy, do a 'Restart' of the computer (not a shutdown), and then reinstall Speccy from scratch.
You can download the installer here: https://www.ccleaner.com/speccy/builds
Don't forget to make a note of your licence details if you have a licence, you'll need to re-register the new install.