Safe to delete index.dat files?

Hi, I'm new to the forums.

Is it safe to delete the index.dat files with CCleaner?

I was also wondering what the "Last download location" on CCleaner is. Thanks

You may find the documentation links helpful for some of your questions.

http://www.piriform.com/docs/ccleaner/ccleaner-rules/windows-tab/internet-explorer-files

Welcome to the forum Lynchy :)