My system with Windows XP is not operational after CCleaner execution.
ProcessExplorer utility (SystemInternals) presents rundll32.exe process in freeze state with line command "RunDll32.exe InetCpl.cpl,ClearMyTracksByProcess 16" or "RunDll32.exe InetCpl.cpl,ClearMyTracksByProcess 32".
CCLeaner now uses IE's inbuilt removal techniques, as has been true for many versions now, however this change may be why previous version would act as a work around.
If you have your Windows XP installation CD or the setup files stored on the hard disk you could try refreshing the system dllcache with correct and clean Microsoft versions, this can sometimes fix crashes/errors:
1. Insert the Windows XP install CD into your CD/DVD drive.
2. Click Start, Run, and type in: sfc /purgecache
3. Click Start, Run, and type in: sfc /scannow
4. After System File Checker has finished restart your computer.