When CCleaner Option, "Run CCleaner when the computer starts" is checked, and the options are NOT stored in an INI file, an entry is created in HKCU\Software\Microsoft\Windows\CurrentVersion\Run. This would suggest the option should be titled, "Run CCleaner when the current user (who sets this option) logs on."
On multi-user home systems, I've had several folks tell me that CCleaner is not running even though the "Owner" set it to run "when the computer starts." It would be useful to have a CCleaner option to clear all the user profiles according to either a master profile or as set by each user but I suppose that would be too complicated? Otherwise, perhaps the wording of the option could be updated in a future release.