This problem has returned.
If you create a print file but leave it pending, and then run CCleaner, after that the file could have gone.
Unless you are running CCleaner whilst you are simultaneously printing, I do not see how CCleaner could be responsible for deleting the print file whilst it is being created.
If you have seen the file being created and immediately lost / deleted, perhaps :-
1. The printer drivers have read all the data "instantly" and signalled completion without actually putting ink to paper;
2. Something strange happened to the registry.
Possibly causes might be a Windows security patch, or cleaning the registry.
I always protect myself by having Windows update totally disabled until every-one else has had a few days to complain if the latest security patches cause problems, and then before enabling the update I archive a disc image ready for an instant restoration should I wish.
Additionally, I never clean the registry without first agonising over the possible consequences of each item, and only then do I clean with the backup option selected.
Regards
Alan