please help ~ cant access external hardrive files

Hello ~ Help!

Today I did a CC cleaner free space driver wipe on a USB key, in the process, one of my other external hardrives was somehow affected. If I go into its properties it tells me all is well, device is working properly, the allocated space and free space looks good, 101 GB available of 232 GB. but the icon is changed to an unreadable format and if I try to open it, it says it is empty. If I try to remove it, it tell me it is in use.

All my work is on this drive ~ please can anyone help ~ I don't want to try anything that might make it worse. It is a La Cie Hardrive USb

Have you rebooted yet?