What is already implemented is fine if I really know that I never want a particular thing to run on start-up, but not so good if I am uncertain or later wish to backtrack.
When cleaning the issues from the registry there is the option to create REG files for a subsequent undo.
It would be nice if Tools -> Startup did something similar, at least for the HKCU:Run and HKLM:Run items.
An even nicer feature in RegSeeker is to disable a start-up. I think this tweaks the registry so the chosen item does not start-up, BUT for a subsequent undo you only have to look in Regseeker and the disabled item is now shown as disabled, and ready to be enabled again WITHOUT having to look in "My Documents" and trying to remember which of the many REG files is what you should not have done last week !!!
Regards
Alan