miscellaneous caches box on ccleaner mac

CCleaner for Mac
1

Hi All

on the mac ccleaner apparently the miscellaneous caches box deletes the below areas as kindly supplied by group member 'hulk' so thank you. my question is is it safe to leave the miscellaneous caches box ticked?

~/Library/Caches

/Library/Caches

/private/var/folders/.../-Caches-/

2

thank you sir, that knowledge is well useful :)