After restarting your system have a look in your temp folder locations such as the Windows\Temp folder and your UserProfile\Temp folder, and try to determine if your IR mouse/keyboard is by chance putting some driver file in that/those folder(s) such as an .EXE file or some other file. Some hardware for whatever odd reason will do this and deleting the file they expect to be in there can cause an issue.
Now if you find a file placed in the temp folder that's possibly required you can then exclude it from being cleaned by CCleaner by: