I respect your caution.
On Windows 7 Ultimate I took initially no risks whilst I struggled with all the differences between it and XP.
I am now more confident with Win 7 but have not been aggravated my any problems with "?:\system volume information".
This may be because I have disabled all volume monitoring (or whatever Win 7 calls it) and all drives.
Therefore I have not taken action against them and there is one instance (with "no access") on each of my partitions.
Although Windows Explorer reports "?:\system volume information is not accessible" when I try to open any of them,
Treesize Free shows me that "C:\system volume information\Syscache.hve" is 3.25 MB (3,407,872 bytes) and was Accessed 02 December 2012, 22:31:06
and can also show me 4 other files and 3 further sub-folders and files,
including "C:\system volume information\ChkDdsk\Chkdsk20110808110721.log"
I would not dream of tampering with "C:\system volume information\"
I do not remember seeing anything like "C:\system volume information\Syscache.hve" on XP,
and the Chkdsk*.log files were not held there either.
I spent several years with "?:\system volume information\" exterminated on XP and never had grief.
Windows 7 and possibly Vista seems to have a few other odd things they put there