I have run Defraggler at least a dozen times and it has not defragmented the drive. I use "Defrag checked" and analyzed after word to make sure no fragmentation was reported. I then run defrag and it resulted in 138 fragmented files. Need to go back to the drawing board on this one, Windows actually does a better job.
check that you have the three boxes in the screen shot (link below) ticked, and the bottom one unticked.
https://forum.piriform.com/index.php?showtopic=35458&p=212223