I had to re-install my OS (Windows XP Prof. SP2) and all apps and data due to a hard drive problem. The last thing I installed was CCleaner. After I install a program I always restart my system before I use the program or continue installing other apps. After I installed CCleaner and restarted my system, my antivirus program was disabled! I'm using BitDefender 10. Prior to to installing CCleaner, I'd installed several other programs with no effect whatsoever on my antivirus program. I can only conclude that CCleaner did this. I un-installed CCleaner immediately and will not use it again.