Conservative Settings for a Clean in portable

Hi fellows. I'm using the portable version on my laptop for the 1st time, I'm a bit apprehensive b4 performing the clean. So I just wanna run the following couple of qns by your fellows b4 executing a clean:

1. This is the ONLY "area" I'm gonna clean (I manage my web browser temp files manually, so I dun touch those):

CCleaner.JPG

In case the image can't be seen, I only have Temp. files, ClipBoard Memory Dump, Chkdisk file fragments & windows log files under System checked for cleaning

Is it too conservative? In advanced, I allow cleaning of temp files of <48hrs, is that safe?

2. Generally speaking, can I safely say that ALL files inside "C:\Documents and Settings\%username%\Local Settings\Temp" & "C:\Windows\Temp" can be safely deleted without any worry?

3. Can somebody briefly explain to me wat these directories are involved for? I'm gonna clean them:

\Local Settings\Temp\MessengerCache\

\Local Settings\Temp\NeroDemo10225\

\Local Settings\Temp\Patcher\

C:\WINDOWS\TEMP\LPDIR\

C:\WINDOWS\TEMP\WGANotify.settings

Particularly the 1st 3, cos I've lotsa entries for those, after running an analysis...wat'll deleting the files in them do?

4. Deleting my Windows Update kb***** logs will not screw up my Windows Update right?

Thanks. Hope to learn something in-depth here...

Have a read through the beginners guide and if you still have questions come back and ask away ;) :

http://www.ccleanerbeginnersguide.com/

Have a read through the beginners guide and if you still have questions come back and ask away ;) :

http://www.ccleanerbeginnersguide.com/

I read thru the beginners' guide, but it doesn't explain qn3 & 4, which I'm keen to learn about.