I just downloaded and ran Defraggler on a Vista 64 machine. The program stated 230GB Free Space, 174GB Used Space and 39% fragmented (67.9GB). Thinking this was likely from my Zune and all my podcasts I could see it however I do run the Windows defrag montly? Defraggler ran for about 12+ hours, no errors. Once it completed It stated 27% fragmented so ran the Analyze on the drive again and it still claimed 39% fragged?