Cleanup corrupted Quicken

I installed CCleaner Pro and ran cleanup. Quicken worked fine at that point. A couple of days later, a box popped up saying I could regain 1 GB of drive space by running cleanup. I ran it and immediately after that I tried to generate some reports in Quicken. The reports produced corrupted results. I restarted my computer, and the reports were as they should be. Later, after resuming from Sleep I discovered the same problem. It looks like I will have to do a re-install and install all the updates. After doing that, how would I protect Quicken from having this happen again, other than never cleaning my drive again?

16/03/24

After another restart, the problem seems to have gone away.