The main window opens and when I pick analyze, the system returned the error "ccleaner stopped working". I then uninstalled, redownloaded 5.22 and now it fails to run at all. I'm on Windows 10.
Can you make sure that there is not an instance of CCleaner already running by looking in the Windows task Manager.
Can you uninstall again (sorry!!) and install the slim version from here and tell us if that works.