It appears that immediately after install I am able to 'run cleaner' successfully. Any subsequent attempts to use the program however result in the error msg 'windows cannot access the specified device path or file. You may not have the appropriate permissions to access them'. I am using a standalone PC at home running XP sp3 and this happens even when running the program direct from its install folder and regardless of whether or not I stay logged on following install or reboot. Can anyone help me please?