ccleaner no long work in window 10

i use to have ccleaner working in window 10, but of late is does not all i get is ( window can not access file ) i tryed runing program as administrator, but that does not work either

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Have you tried uninstalling and then and reinstalling it?

I don't see CCleaner in your screenshot (I do however see Avast)

You can download latest version from here

https://www.ccleaner.com/ccleaner/builds