CCleaner & Indexing Service

Could CCleaner interfere with Indexing Service on XP?

I go to START > SEARCH. I try searching for a specific file name or word in a specific folder (for example, a folder of PDF files), and get absolutely nothing coming back. Yes, I've checked the accuracy of the file name, of my spelling, and the search options (case-sensitive or not).

This only seems to have started happening since I downloaded CCleaner.

Is something checked in the Cleaner or Registry options which should not be . . . ???

I'm using XP SP3.

Thanks.