I run CCleaner portable quite frequently, but it seems that Piriform has changed things so that it will only run as someone with administrative rights? Is that true, or am I missing something, because due to this limitation, CCleaner does not work anymore, and I will have to find an alternative.
No, I am not getting an error, and the skip UAC option was turned on, and I was still getting the UAC asking me to input the credentials of an administrator.
If it's a shortcut pointing to CCleaner that you made sometime ago, perhaps create a brand new shortcut pointing to it - now I don't know if this will make any difference however it's worth a try.