Please allow me to explain my point of view.
Throughout this topic my position has been, and remains, that ANY anti-malware product,
(including but not restricted to Kaspersky,)
may suffer with a False Positive and wrongly finger an innocent item as "malware",
and if this same "protective" product is then invited to delete or "disinfect" the so called "malware" then some truly beneficial feature will have been destroyed.
The consequence of that destruction could range from the loss of some cleaning capability or the removal of some needed protection,
specifically it could remove :-
the contents of CCleaner / Options / Include, thus reducing the cleansing capabilities;
the contents of CCleaner / Options / Exclude, thus endangering the protection required for continued correct operation of some installed software;
OR removal of Piriform defined capabilities that are built into CCleaner.EXE regardless of any WinApp2.ini or User GUI customisation.
I am quite certain that any reputable "protective product" has the ability to put out of action some feature of CCleaner,
and in so doing will blunt its surgical precision in "Junk removal".
In view of Nergal's post I would suggest that amongst thousands of other possibilities,
perhaps the "protective product" has damaged the capability of "Complex overwrite (7 pass)" deletion or one all of the other options.
Rather than take pot-shots at many possibilities,
I advocate a fresh install of CCleaner whilst the "protective product" is free from False Positives,
and I never consider any product installation to be clean and free from the effects of previous False Positive actions,
unless the previous damaged installation is totally un-installed.
N.B. I cannot remember the name of the AntiVirus product,
but there was one in the last few years which had a bad signature update,
and many people lost total functionality until they re-installed and re-registered applications or system files.