Latest CC 4.08.4428 (x64) is always breaking Chrome v32 (32.0.1700.41) settings file after cleaning. Windows 7/x64. CC/Chrome settings: Internet cache, internet history, download history, last download location, session, compact databases. After running CC with these settings, when Chrome starts it complains for broken settings file and resets to defaults.
BTW, this problem was never noticed before with older CC releases.
I hope it helps!