I have been experiencing the same problem with CCleaner not opening. I use MicroTrend for my security software. When I right clicked on MicroTrend and clicked on the check for updates line, it told me I was completely up to date. But, when I went online to the home page for MicroTrend to see if I could find a forum like this one where someone was experiencing the same problem, I noticed that there was a place to click on to "grab" the 2020 update to my TrendMicro program. I clicked on that, downloaded and installed the 2020 update, and my problem opening CCleaner went away.