Using Windows 10 Version 1903 Built 18362.356, Microsoft Outlook 2010 (14.0.7236.5000) SP2 MSO (14.0.7237.500) and Google Chrome (Version 77.0.3865.90) as Standard-Browser.
A Registry clean with CCleaner Free v5.61.7392 (64bit) result in a deleted Registry Key
"C:\Program Files\Internet Explorer\IEXPLORE.EXE" %1 HKCR\htmlfile\shell\open
what cause this problem
Hyperlinks are not working in Outlook
I could resove the problem with Method 3: Export and import the registry key from another computer
It would be great if you leave this key untouched with the next realease.