No.
However, the same problem existed with v5.44 as well.
I am happy to report that starting with v5.45, it looks like Piriform has fixed whatever the issue was with 5.42, 5.43 and 5.44.
CCleaner v5.45 now appears to work once again on Windows 2003, 2008 and 2012 server.
Now with Windows Server 2016, CCleaner identifies it as "Windows 10".
Anyone else seen this?