i came to the forums to see if anyone else was having this very same issue, and lo and behold!
i have never had this happen in years of using ccleaner, but it is definitely noticeable - when i read some people quoting it may take a second or two more... no, i wouldn't have come here about a very short period of time. i am guessing that the delay from when ccleaner opens (with greyed out buttons) to when the two main buttons ("analyze" and "run cleaner") are blue and ready to use, would be approximately 15 seconds. it may not sound like much, which it really isn't, but i'm used to ccleaner popping up and being ready to use immediately!
i am glad to see that i'm not the only one that noticed something dramatic changed over the last while.
hopefully a solution can be found.
i am using windows 8.1 x64, if you have any other questions about my configuration, i can provide if necessary.
thank you for looking into this Piriform! it is such a great utility.