Windows 10 cannot access ccsetup582.exe in CCleaner Help Requests Posted July 21 That's a network error saying that a server cannot be contacted for whatever reason. The server could be down, your AV/firewall may be blocking access, something else between you and that particular server (eg. your internet service provider) may be having a problem. The latest CCleaner is v5.83.9050. I suggest that you download the 'Slim' installer from here (3rd one down) and use that to install the latest CCleaner:https://www.piriform.com/ccleaner/builds (That 'Slim' installer installs exactly the same CCleaner but it doesn't try to contact the same servers during the installation).